Assessment of Fasudil on Contrast-Associated Acute Kidney Injury Using Multiparametric Renal MRI

Assessment of Fasudil on Contrast-Associated Acute Kidney Injury Using Multiparametric Renal MRI

Aims: To evaluate the utility of fasudil in a rat model of contrast-associated acute kidney injury (CA-AKI) and explore its underlying mechanism through multiparametric renal magnetic resonance imaging (mpMRI).Methods: Experimental rats (n = 72) were grouped as follows: controls (n = 24), CA-AKI (n...

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Bibliographic Details
Main Authors: Bin Wang, Yongfang Wang, Yan Tan, Jinxia Guo, Haoyuan Chen, Pu-Yeh Wu, Xiaochun Wang, Hui Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-06-01
Series:Frontiers in Pharmacology
Subjects:
CA-AKI
fasudil
multiparametric MRI
Rho/ROCK
renal hypoxia
renal fibrosis
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.905547/full

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https://www.frontiersin.org/articles/10.3389/fphar.2022.905547/full

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