M1-derived extracellular vesicles polarize recipient macrophages into M2-like macrophages and alter skeletal muscle homeostasis in a hyper-glucose environment

M1-derived extracellular vesicles polarize recipient macrophages into M2-like macrophages and alter skeletal muscle homeostasis in a hyper-glucose environment

Abstract Background Macrophages release not only cytokines but also extracellular vesicles (EVs). which are small membrane-derived nanovesicles with virus-like properties transferring cellular material between cells. Until now, the consequences of macrophage plasticity on the release and the composi...

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Main Authors: Stefano Tacconi, Francesco Vari, Carolina Sbarigia, Diana Vardanyan, Serena Longo, Francesco Mura, Federica Angilè, Audrey Jalabert, Ferninand Blangero, Assia Eljaafari, Laurence Canaple, Daniele Vergara, Francesco Paolo Fanizzi, Marco Rossi, Claire Crola Da Silva, Elizabeth Errazuriz-Cerda, Christel Cassin, Rienk Nieuwland, Anna Maria Giudetti, Sophie Rome, Luciana Dini
Format: Article
Language:English
Published: BMC 2024-03-01
Series:Cell Communication and Signaling
Subjects:
Extracellular vesicles
Hyperglycemia
Macrophage
Lipid metabolism
Skeletal muscle
Oxidative phosphorylation
Online Access:https://doi.org/10.1186/s12964-024-01560-7

Internet

https://doi.org/10.1186/s12964-024-01560-7

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