Drosophila FGFR/Htl signaling shapes embryonic glia to phagocytose apoptotic neurons

Abstract Glial phagocytosis of apoptotic neurons is crucial for development and proper function of the central nervous system. Relying on transmembrane receptors located on their protrusions, phagocytic glia recognize and engulf apoptotic debris. Like vertebrate microglia, Drosophila phagocytic glia...

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Bibliographic Details
Main Authors: Malak Ayoub, Li-mor David, Boris Shklyar, Ketty Hakim-Mishnaevski, Estee Kurant
Format: Article
Language:English
Published: Nature Publishing Group 2023-03-01
Series:Cell Death Discovery
Online Access:https://doi.org/10.1038/s41420-023-01382-5