Coexistence of blaKPC-2 and blaNDM-1 in one IncHI5 plasmid confers transferable carbapenem resistance from a clinical isolate of Klebsiella michiganensis in China

ABSTRACT: Objectives: This study firstly identified an IncHI5 plasmid pK254-KPC_NDM co-carrying two different class carbapenemase genes blaKPC-2 and blaNDM-1 in Klebsiella michiganensis K254. Methods: The strain K254 was sequenced by high-throughput genome sequencing. A detailed genomic and phenoty...

Full description

Bibliographic Details
Main Authors: Xinhua Luo, Fang Dong, Piaopiao Dai, Mengqiao Xu, Lianhua Yu, Dakang Hu, Jiao Feng, Jin Zhang, Ying Jing
Format: Article
Language:English
Published: Elsevier 2023-12-01
Series:Journal of Global Antimicrobial Resistance
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S2213716523001510