Optimal controlling of anti-TGF- $$\beta$$ β and anti-PDGF medicines for preventing pulmonary fibrosis

Abstract In the repair of injury, some transforming growth factor- $$\beta$$ β s (TGF- $$\beta$$ β s) and platelet-derived growth factors (PDGFs) bind to fibroblast receptors as ligands and cause the differentiation of fibroblasts into myofibroblasts. When the injury repair is repeated, the myofibro...

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Bibliographic Details
Main Authors: Fatemeh Bahram Yazdroudi, Alaeddin Malek
Format: Article
Language:English
Published: Nature Portfolio 2023-09-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41294-z