Optimal controlling of anti-TGF- $$\beta$$ β and anti-PDGF medicines for preventing pulmonary fibrosis
Abstract In the repair of injury, some transforming growth factor- $$\beta$$ β s (TGF- $$\beta$$ β s) and platelet-derived growth factors (PDGFs) bind to fibroblast receptors as ligands and cause the differentiation of fibroblasts into myofibroblasts. When the injury repair is repeated, the myofibro...
Main Authors: | , |
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Format: | Article |
Language: | English |
Published: |
Nature Portfolio
2023-09-01
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Series: | Scientific Reports |
Online Access: | https://doi.org/10.1038/s41598-023-41294-z |