GPR110 (ADGRF1) mediates anti-inflammatory effects of N-docosahexaenoylethanolamine

GPR110 (ADGRF1) mediates anti-inflammatory effects of N-docosahexaenoylethanolamine

Abstract Background Neuroinflammation is a widely accepted underlying condition for various pathological processes in the brain. In a recent study, synaptamide, an endogenous metabolite derived from docosahexaenoic acid (DHA, 22:6n-3), was identified as a specific ligand to orphan adhesion G-protein...

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Bibliographic Details
Main Authors: Taeyeop Park, Huazhen Chen, Hee-Yong Kim
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Journal of Neuroinflammation
Subjects:
GPR110
Synaptamide
cAMP
Neuroinflammation
NF-κB
Docosahexaenoic acid
Online Access:http://link.springer.com/article/10.1186/s12974-019-1621-2

Internet

http://link.springer.com/article/10.1186/s12974-019-1621-2

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