Cadmium induces epithelial–mesenchymal transition and migration of renal cancer cells by increasing PGE2 through a cAMP/PKA-COX2 dependent mechanism

Environmental or occupational exposure of Cadmium (Cd) is concerned to be a threat to human health. The kidney is main target of Cd accumulation, which increases the risk of renal cell carcinoma (RCC). In addition, low content of Cd had been determined in kidney cancer, however, the roles of presenc...

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Bibliographic Details
Main Authors: Haifeng Shi, Xi Sun, Anqi Kong, Haiyan Ma, Yimin Xie, Dongrui Cheng, Chris Kong Chu Wong, Yang Zhou, Jie Gu
Format: Article
Language:English
Published: Elsevier 2021-01-01
Series:Ecotoxicology and Environmental Safety
Subjects:
Online Access:http://www.sciencedirect.com/science/article/pii/S0147651320313178