Therapeutic miR-506-3p Replacement in Pancreatic Carcinoma Leads to Multiple Effects including Autophagy, Apoptosis, Senescence, and Mitochondrial Alterations In Vitro and In Vivo

Therapeutic miR-506-3p Replacement in Pancreatic Carcinoma Leads to Multiple Effects including Autophagy, Apoptosis, Senescence, and Mitochondrial Alterations In Vitro and In Vivo

Pancreatic ductal adenocarcinoma (PDAC) is a leading cause of cancer mortality. Considering its very poor prognosis, novel treatment options are urgently needed. MicroRNAs (miRNAs) are involved in the regulation of various physiological and pathological processes. In tumors, aberrant downregulation...

Full description

Bibliographic Details
Main Authors: Hannes Borchardt, Alexander Kogel, Hermann Kalwa, Ulrike Weirauch, Achim Aigner
Format: Article
Language:English
Published: MDPI AG 2022-07-01
Series:Biomedicines
Subjects:
miR-506
pancreatic cancer
miRNA replacement therapy
miRNA
Online Access:https://www.mdpi.com/2227-9059/10/7/1692

Internet

https://www.mdpi.com/2227-9059/10/7/1692

Similar Items