Intraarterial Transplantation of Mitochondria After Ischemic Stroke Reduces Cerebral Infarction

Intraarterial Transplantation of Mitochondria After Ischemic Stroke Reduces Cerebral Infarction

Background Transplantation of autologous mitochondria into ischemic tissue may mitigate injury caused by ischemia and reperfusion. Methods Using murine stroke models of middle cerebral artery occlusion, we sought to evaluate feasibility of delivery of viable mitochondria to ischemic brain parenchyma...

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Bibliographic Details
Main Authors: Pedro Norat, Jennifer D. Sokolowski, Catherine M. Gorick, Sauson Soldozy, Jeyan S. Kumar, Youngrok Chae, Kaan Yagmurlu, Joelle Nilak, Khadijeh A. Sharifi, Melanie Walker, Michael R. Levitt, Alexander L. Klibanov, Zhen Yan, Richard J. Price, Petr Tvrdik, Mohammad Yashar S. Kalani
Format: Article
Language:English
Published: Wiley 2023-05-01
Series:Stroke: Vascular and Interventional Neurology
Subjects:
cerebral
focused ultrasound
ischemia
mitochondria
stroke
transplantation
Online Access:https://www.ahajournals.org/doi/10.1161/SVIN.122.000644

Internet

https://www.ahajournals.org/doi/10.1161/SVIN.122.000644

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