Re-evaluation of publicly available gene-expression databases using machine-learning yields a maximum prognostic power in breast cancer

Abstract Gene expression signatures refer to patterns of gene activities and are used to classify different types of cancer, determine prognosis, and guide treatment decisions. Advancements in high-throughput technology and machine learning have led to improvements to predict a patient’s prognosis f...

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Bibliographic Details
Main Authors: Dimitrij Tschodu, Jürgen Lippoldt, Pablo Gottheil, Anne-Sophie Wegscheider, Josef A. Käs, Axel Niendorf
Format: Article
Language:English
Published: Nature Portfolio 2023-10-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-023-41090-9