Extracellular vesicle‐associated cholesterol supports the regenerative functions of macrophages in the brain

Extracellular vesicle‐associated cholesterol supports the regenerative functions of macrophages in the brain

Abstract Macrophages play major roles in the pathophysiology of various neurological disorders, being involved in seemingly opposing processes such as lesion progression and resolution. Yet, the molecular mechanisms that drive their harmful and benign effector functions remain poorly understood. Her...

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Bibliographic Details
Main Authors: Sam Vanherle, Jeroen Guns, Melanie Loix, Fleur Mingneau, Tess Dierckx, Flore Wouters, Koen Kuipers, Tim Vangansewinkel, Esther Wolfs, Paula Pincela Lins, Annelies Bronckaers, Ivo Lambrichts, Jonas Dehairs, Johannes V. Swinnen, Sanne G. S. Verberk, Mansour Haidar, Jerome J. A. Hendriks, Jeroen F. J. Bogie
Format: Article
Language:English
Published: Wiley 2023-12-01
Series:Journal of Extracellular Vesicles
Subjects:
cholesterol
extracellular vesicle
oligodendrocyte precursor cell differentiation
remyelination
repair‐associated macrophage
Online Access:https://doi.org/10.1002/jev2.12394

Internet

https://doi.org/10.1002/jev2.12394

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