Abnormal habenula functional connectivity characterizes treatment-resistant depression

Abnormal habenula functional connectivity characterizes treatment-resistant depression

Background: A significant proportion of patients with major depressive disorder are resistant to antidepressant medication and psychological treatments. A core symptom of treatment-resistant depression (TRD) is anhedonia, or the inability to feel pleasure, which has been attributed to disrupted habe...

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Bibliographic Details
Main Authors: Ana Rita Barreiros, Isabella Breukelaar, Prashanth Mayur, Jagadeesh Andepalli, Yoshiro Tomimatsu, Kenta Funayama, Sheryl Foster, Philip Boyce, Gin S. Malhi, Anthony Harris, Mayuresh S. Korgaonkar
Format: Article
Language:English
Published: Elsevier 2022-01-01
Series:NeuroImage: Clinical
Subjects:
Treatment-resistant depression
Treatment-sensitive depression
Functional connectivity
resting-state fMRI
Habenula
Anhedonia
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158222000559

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http://www.sciencedirect.com/science/article/pii/S2213158222000559

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