Antimicrobial Activity and DFT Studies of a Novel Set of Spiropyrrolidines Tethered with Thiochroman-4-one/Chroman-4-one Scaffolds

Antimicrobial Activity and DFT Studies of a Novel Set of Spiropyrrolidines Tethered with Thiochroman-4-one/Chroman-4-one Scaffolds

A novel series of 14 spiropyrrolidines bearing thiochroman-4-one/chroman-4-one, and oxindole/acenaphthylene-1,2-dione moieties were synthesized and characterized by spectroscopic techniques, as well as by three X-ray diffraction studies, corroborating the stereochemistry. Quantum chemical calculatio...

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Bibliographic Details
Main Authors: Nourhène Chouchène, Amani Toumi, Sarra Boudriga, Hayet Edziri, Mansour Sobeh, Mohamed A. O. Abdelfattah, Moheddine Askri, Michael Knorr, Carsten Strohmann, Lukas Brieger, Armand Soldera
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:Molecules
Subjects:
[3+2] cycloaddition
thiochroman-4-one
chroman-4-one
spiropyrrolidine
crystal structure
DFT
Online Access:https://www.mdpi.com/1420-3049/27/3/582

Internet

https://www.mdpi.com/1420-3049/27/3/582

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