Modulatory effect of MG-132 proteasomal inhibition on boar sperm motility during in vitro capacitation

Modulatory effect of MG-132 proteasomal inhibition on boar sperm motility during in vitro capacitation

A series of biochemical and biophysical changes during sperm capacitation initiates various signaling pathways related to protein phosphorylation leading to sperm hyperactivation, simultaneously with the regulation of proteasomal activity responsible for protein degradation and turnover. Our study a...

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Bibliographic Details
Main Authors: Lenka Hackerova, Barbora Klusackova, Michal Zigo, Natalie Zelenkova, Katerina Havlikova, Romana Krejcirova, Marketa Sedmikova, Peter Sutovsky, Katerina Komrskova, Pavla Postlerova, Ondrej Simonik
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-03-01
Series:Frontiers in Veterinary Science
Subjects:
ubiquitin-proteasome system
hyperactivation
phosphorylation
reproduction
sperm physiology
cluster analysis
Online Access:https://www.frontiersin.org/articles/10.3389/fvets.2023.1116891/full

Internet

https://www.frontiersin.org/articles/10.3389/fvets.2023.1116891/full

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