Immunohistochemical scoring of LAG-3 in conjunction with CD8 in the tumor microenvironment predicts response to immunotherapy in hepatocellular carcinoma
IntroductionImmune checkpoint blockade (ICB) is a systemic therapeutic option for advanced hepatocellular carcinoma (HCC). However, low patient response rates necessitate the development of robust predictive biomarkers that identify individuals who will benefit from ICB. A 4-gene inflammatory signat...
المؤلفون الرئيسيون: | , , , , , , , , , , , , , , , , , , |
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التنسيق: | مقال |
اللغة: | English |
منشور في: |
Frontiers Media S.A.
2023-06-01
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سلاسل: | Frontiers in Immunology |
الموضوعات: | |
الوصول للمادة أونلاين: | https://www.frontiersin.org/articles/10.3389/fimmu.2023.1150985/full |