Production of the HBc Protein from Different HBV Genotypes in <i>E. coli</i>. Use of Reassociated HBc VLPs for Packaging of ss- and dsRNA
The core proteins (HBc) of the hepatitis B virus (HBV) genotypes A, B, C, D, E, F, and G were cloned and expressed in <i>Escherichia coli (E. coli</i>), and HBc-formed virus-like particles (VLPs) were purified with ammonium sulfate precipitation, gel filtration, and ion exchange chromato...
Main Authors: | , , , , , , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2021-01-01
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Series: | Microorganisms |
Subjects: | |
Online Access: | https://www.mdpi.com/2076-2607/9/2/283 |