Production of the HBc Protein from Different HBV Genotypes in <i>E. coli</i>. Use of Reassociated HBc VLPs for Packaging of ss- and dsRNA

The core proteins (HBc) of the hepatitis B virus (HBV) genotypes A, B, C, D, E, F, and G were cloned and expressed in <i>Escherichia coli (E. coli</i>), and HBc-formed virus-like particles (VLPs) were purified with ammonium sulfate precipitation, gel filtration, and ion exchange chromato...

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Bibliographic Details
Main Authors: Ivars Petrovskis, Ilva Lieknina, Andris Dislers, Juris Jansons, Janis Bogans, Inara Akopjana, Jelena Zakova, Irina Sominskaya
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Microorganisms
Subjects:
Online Access:https://www.mdpi.com/2076-2607/9/2/283