Physiactisome: A New Nanovesicle Drug Containing Heat Shock Protein 60 for Treating Muscle Wasting and Cachexia

Physiactisome: A New Nanovesicle Drug Containing Heat Shock Protein 60 for Treating Muscle Wasting and Cachexia

Currently, no commercially available drugs have the ability to reverse cachexia or counteract muscle wasting and the loss of lean mass. Here, we report the methodology used to develop Physiactisome—a conditioned medium released by heat shock protein 60 (Hsp60)—overexpressing C2C12 cell lines enriche...

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Bibliographic Details
Main Authors: Valentina Di Felice, Rosario Barone, Eleonora Trovato, Daniela D’Amico, Filippo Macaluso, Claudia Campanella, Antonella Marino Gammazza, Vera Muccilli, Vincenzo Cunsolo, Patrizia Cancemi, Gabriele Multhoff, Dario Coletti, Sergio Adamo, Felicia Farina, Francesco Cappello
Format: Article
Language:English
Published: MDPI AG 2022-04-01
Series:Cells
Subjects:
cachexia
muscle atrophy
exercise
exosome
muscle wasting
sarcopenia
Online Access:https://www.mdpi.com/2073-4409/11/9/1406

Internet

https://www.mdpi.com/2073-4409/11/9/1406

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