Reassessment of amphetamine- and phencyclidine-induced locomotor hyperactivity as a model of psychosis-like behavior in rats

Locomotor hyperactivity induced by psychotomimetic drugs, such as amphetamine and phencyclidine, is widely used as an animal model of psychosis-like behaviour and is commonly attributed to an interaction with dopamine release and N-methyl-D-aspartate (NMDA) receptors, respectively. However, what...

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Bibliographic Details
Main Authors: Snezana Kusljic, Maarten van den Buuse, Andrea Gogos
Format: Article
Language:English
Published: IMR Press 2022-01-01
Series:Journal of Integrative Neuroscience
Subjects:
Online Access:https://article.imrpress.com/journal/JIN/21/1/10.31083/j.jin2101017/1757-448X-21-1-017.pdf