Translation of in vitro-transcribed RNA therapeutics

Translation of in vitro-transcribed RNA therapeutics

In vitro transcribed, modified messenger RNAs (IVTmRNAs) have been used to vaccinate billions of individuals against the SARS-CoV-2 virus, and are currently being developed for many additional therapeutic applications. IVTmRNAs must be translated into proteins with therapeutic activity by the same c...

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Bibliographic Details
Main Authors: Tobias von der Haar, Thomas E. Mulroney, Fabio Hedayioglu, Sathishkumar Kurusamy, Maria Rust, Kathryn S. Lilley, James E. Thaventhiran, Anne E. Willis, C. Mark Smales
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-02-01
Series:Frontiers in Molecular Biosciences
Subjects:
RNA therapeutic
translation
protein synthesis
translational control
RNA vaccines
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2023.1128067/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2023.1128067/full

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