Generation of circulating autoreactive pre-plasma cells fueled by naive B cells in celiac disease

Generation of circulating autoreactive pre-plasma cells fueled by naive B cells in celiac disease

Summary: Autoantibodies against the enzyme transglutaminase 2 (TG2) are characteristic of celiac disease (CeD), and TG2-specific immunoglobulin (Ig) A plasma cells are abundant in gut biopsies of patients. Here, we describe the corresponding population of autoreactive B cells in blood. Circulating T...

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Bibliographic Details
Main Authors: Ida Lindeman, Lene S. Høydahl, Asbjørn Christophersen, Louise F. Risnes, Jørgen Jahnsen, Knut E.A. Lundin, Ludvig M. Sollid, Rasmus Iversen
Format: Article
Language:English
Published: Elsevier 2024-04-01
Series:Cell Reports
Subjects:
CP: Immunology
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124724003735

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http://www.sciencedirect.com/science/article/pii/S2211124724003735

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