Association of Genomic Instability Score, Tumor Mutational Burden, and Tumor-Infiltrating Lymphocytes as Biomarkers in Uterine Serous Carcinoma

Association of Genomic Instability Score, Tumor Mutational Burden, and Tumor-Infiltrating Lymphocytes as Biomarkers in Uterine Serous Carcinoma

Background: Uterine serous carcinomas represent 10% of uterine carcinomas but account for nearly 40% of deaths from the disease. Improved molecular characterization of these tumors is instrumental in guiding targeted treatment and improving outcomes. This study assessed the genomic instability score...

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Bibliographic Details
Main Authors: Elizabeth A. Bloom, Pamela N. Peters, Regina Whitaker, Shonagh Russell, Benjamin Albright, Shelly Cummings, Kirsten M. Timms, Thomas Slavin, Braden Probst, Kyle C. Strickland, Rebecca A. Previs
Format: Article
Language:English
Published: MDPI AG 2023-01-01
Series:Cancers
Subjects:
uterine serous cancer
tumor mutational burden
genomic instability
tumor-infiltrating lymphocytes
immunohistochemistry
Online Access:https://www.mdpi.com/2072-6694/15/2/528

Internet

https://www.mdpi.com/2072-6694/15/2/528

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