Comparative Investigation into the Roles of Imipenem:Cyclodextrin Complexation and Antibiotic Combination in Combatting Antimicrobial Resistance in Gram-Negative Bacteria

Comparative Investigation into the Roles of Imipenem:Cyclodextrin Complexation and Antibiotic Combination in Combatting Antimicrobial Resistance in Gram-Negative Bacteria

Extensively drug-resistant (XDR), multidrug-resistant (MDR) and pandrug-resistant (PDR) Gram-negative microorganisms (GNBs) are considered a significant global threat. β-lactam and aminoglycoside combinations and imipenem:cyclodextrin inclusion complexes were studied for the treatment of lethal GNBs...

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Bibliographic Details
Main Authors: Sara Mahmoud Farhan, Rehab Mahmoud Abd El-Baky, Hala Rady Ahmed, Zeinab Fathalla, Ali Alamri, Hamdy Abdelkader, Adel Al Fatease
Format: Article
Language:English
Published: MDPI AG 2023-10-01
Series:Pharmaceuticals
Subjects:
proteus
klebsiella
<i>Acinetobacter baumannii</i>
drug combination
imipenem
amikacin
Online Access:https://www.mdpi.com/1424-8247/16/10/1508

Internet

https://www.mdpi.com/1424-8247/16/10/1508

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