On the Cluster Formation of α-Synuclein Fibrils

On the Cluster Formation of α-Synuclein Fibrils

The dense accumulation of α-Synuclein fibrils in neurons is considered to be strongly associated with Parkinson’s disease. These intracellular inclusions, called Lewy bodies, also contain significant amounts of lipids. To better understand such accumulations, it should be important to study α-Synucl...

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Bibliographic Details
Main Authors: Marija Dubackic, Ilaria Idini, Veronica Lattanzi, Yun Liu, Anne Martel, Ann Terry, Michael Haertlein, Juliette M. Devos, Andrew Jackson, Emma Sparr, Sara Linse, Ulf Olsson
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-10-01
Series:Frontiers in Molecular Biosciences
Subjects:
alpha-synuclein
amyloid fibril
fractal cluster
Lewy bodies (LB)
small-angle neutron scattering (SANS)
rigid-rod cluster modeling
Online Access:https://www.frontiersin.org/articles/10.3389/fmolb.2021.768004/full

Internet

https://www.frontiersin.org/articles/10.3389/fmolb.2021.768004/full

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