Specific Features of Mitochondrial Dysfunction under Conditions of Ferroptosis Induced by <i>t</i>-Butylhydroperoxide and Iron: Protective Role of the Inhibitors of Lipid Peroxidation and Mitochondrial Permeability Transition Pore Opening
Recent studies have indicated the critical importance of mitochondria in the induction and progression of ferroptosis. There is evidence indicating that tert-butyl hydroperoxide (TBH), a lipid-soluble organic peroxide, is capable of inducing ferroptosis-type cell death. We investigated the effect of...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2023-03-01
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Series: | Membranes |
Subjects: | |
Online Access: | https://www.mdpi.com/2077-0375/13/4/372 |