Specific Features of Mitochondrial Dysfunction under Conditions of Ferroptosis Induced by <i>t</i>-Butylhydroperoxide and Iron: Protective Role of the Inhibitors of Lipid Peroxidation and Mitochondrial Permeability Transition Pore Opening

Recent studies have indicated the critical importance of mitochondria in the induction and progression of ferroptosis. There is evidence indicating that tert-butyl hydroperoxide (TBH), a lipid-soluble organic peroxide, is capable of inducing ferroptosis-type cell death. We investigated the effect of...

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Bibliographic Details
Main Authors: Tatiana Fedotcheva, Nikolai Shimanovsky, Nadezhda Fedotcheva
Format: Article
Language:English
Published: MDPI AG 2023-03-01
Series:Membranes
Subjects:
Online Access:https://www.mdpi.com/2077-0375/13/4/372