Unraveling the In Vitro Toxicity Profile of Psychedelic 2C Phenethylamines and Their <i>N</i>-Benzylphenethylamine (NBOMe) Analogues

Unraveling the In Vitro Toxicity Profile of Psychedelic 2C Phenethylamines and Their <i>N</i>-Benzylphenethylamine (NBOMe) Analogues

Mescaline derivative (2C phenethylamines) drugs have been modified by the introduction of a <i>N</i>-2-methoxybenzyl group to originate a new series of compounds with recognized and potent psychedelic effects, the NBOMe-drugs. Although they are prevalent in unregulated drug markets, thei...

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Bibliographic Details
Main Authors: Daniel Martins, Eva Gil-Martins, Fernando Cagide, Catarina da Fonseca, Sofia Benfeito, Carlos Fernandes, Daniel Chavarria, Fernando Remião, Renata Silva, Fernanda Borges
Format: Article
Language:English
Published: MDPI AG 2023-08-01
Series:Pharmaceuticals
Subjects:
new psychoactive substances
2C drugs
NBOMe drugs
SH-SY5Y cells
HepG2 cells
neurotoxicity
Online Access:https://www.mdpi.com/1424-8247/16/8/1158

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https://www.mdpi.com/1424-8247/16/8/1158

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