MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme expression

MiR155-5p in adventitial fibroblasts-derived extracellular vesicles inhibits vascular smooth muscle cell proliferation via suppressing angiotensin-converting enzyme expression

Proliferation of vascular smooth muscle cells (VSMCs) plays crucial roles in vascular remodelling and stiffening in hypertension. Vascular adventitial fibroblasts are a key regulator of vascular wall function and structure. This study is designed to investigate the roles of adventitial fibroblasts-d...

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Bibliographic Details
Main Authors: Xing-Sheng Ren, Ying Tong, Yun Qiu, Chao Ye, Nan Wu, Xiao-Qing Xiong, Jue-Jin Wang, Ying Han, Ye-Bo Zhou, Feng Zhang, Hai-Jian Sun, Xing-Ya Gao, Qi Chen, Yue-Hua Li, Yu-Ming Kang, Guo-Qing Zhu
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Journal of Extracellular Vesicles
Subjects:
microrna
extracellular vesicle
exosome
hypertension
vascular smooth muscle cell
proliferation
angiotensin converting enzyme
Online Access:http://dx.doi.org/10.1080/20013078.2019.1698795

Internet

http://dx.doi.org/10.1080/20013078.2019.1698795

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