An Immunocompetent Environment Unravels the Proto-Oncogenic Role of miR-22

MiR-22 was first identified as a proto-oncogenic microRNA (miRNA) due to its ability to post-transcriptionally suppress the expression of the potent PTEN (Phosphatase And Tensin Homolog) tumor suppressor gene. miR-22 tumorigenic role in cancer was subsequently supported by its ability to positively...

Full description

Bibliographic Details
Main Authors: Maria Laura Centomo, Marianna Vitiello, Laura Poliseno, Pier Paolo Pandolfi
Format: Article
Language:English
Published: MDPI AG 2022-12-01
Series:Cancers
Subjects:
Online Access:https://www.mdpi.com/2072-6694/14/24/6255