Adenosine A2A Receptor Regulates microRNA‐181b Expression in Aorta: Therapeutic Implications for Large‐Artery Stiffness

Adenosine A2A Receptor Regulates microRNA‐181b Expression in Aorta: Therapeutic Implications for Large‐Artery Stiffness

Background The identification of large‐artery stiffness as a major, independent risk factor for cardiovascular disease–associated morbidity and death has focused attention on identifying therapeutic strategies to combat this disorder. Genetic manipulations that delete or inactivate the translin/trax...

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Bibliographic Details
Main Authors: Kei Akiyoshi, Tomonari Fujimori, Xiuping Fu, Aparna P. Shah, Atsushi Yamaguchi, Charles Steenbergen, Lakshmi Santhanam, Dan Berkowitz, Eric Tuday, Jay M. Baraban, Samarjit Das
Format: Article
Language:English
Published: Wiley 2023-07-01
Series:Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Subjects:
adenosine A2A receptor
microRNA
microRNA‐181b
microRNA degradation
translin/trax
vascular stiffness
Online Access:https://www.ahajournals.org/doi/10.1161/JAHA.122.028421

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https://www.ahajournals.org/doi/10.1161/JAHA.122.028421

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