Control of TGFβ signalling by ubiquitination independent function of E3 ubiquitin ligase TRIP12

Abstract Transforming growth factor β (TGFβ) pathway is a master regulator of cell proliferation, differentiation, and death. Deregulation of TGFβ signalling is well established in several human diseases including autoimmune disorders and cancer. Thus, understanding molecular pathways governing TGFβ...

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Bibliographic Details
Main Authors: Kripa S Keyan, Safa Salim, Swetha Gowda, Doua Abdelrahman, Syeda Sakina Amir, Zeyaul Islam, Claire Vargas, Maria Teresa Bengoechea-Alonso, Amira Alwa, Subrat Dahal, Prasanna R. Kolatkar, Sahar Da’as, Jerome Torrisani, Johan Ericsson, Farhan Mohammad, Omar M Khan
Format: Article
Language:English
Published: Nature Publishing Group 2023-10-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-023-06215-y