Changes in nephritogenic serum galactose-deficient IgA1 in IgA nephropathy following tonsillectomy and steroid therapy.

BACKGROUND: Recent studies have shown that galactose-deficient IgA1 (GdIgA1) has an important role in the pathogenesis of IgA nephropathy (IgAN). Although emerging data suggest that serum GdIgA1 can be a useful non-invasive IgAN biomarker, the localization of nephritogenic GdIgA1-producing B cells r...

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Bibliographic Details
Main Authors: Junichiro Nakata, Yusuke Suzuki, Hitoshi Suzuki, Daisuke Sato, Tatsuya Kano, Hiroyuki Yanagawa, Keiichi Matsuzaki, Satoshi Horikoshi, Jan Novak, Yasuhiko Tomino
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3931817?pdf=render