Blocking cholesterol storage to treat Alzheimer’s disease

Cholesterol serves as an essential lipid molecule in various membrane organelles of mammalian cells. The metabolites of cholesterol also play important functions. Acyl-coenzyme A: cholesterol acyltransferase 1 (ACAT1), also named as sterol O-acyltransferase 1, is a membrane-bound enzyme residing at...

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Bibliographic Details
Main Authors: Ta Yuan Chang, Catherine C. Y. Chang, Taylor C. Harned, Adrianna L. De La Torre, Junghoon Lee, Thao N. Huynh, James G. Gow
Format: Article
Language:English
Published: Open Exploration Publishing Inc. 2021-12-01
Series:Exploration of Neuroprotective Therapy
Subjects:
Online Access:https://www.explorationpub.com/Journals/ent/Article/100414