Astragaloside IV promotes pharmacological effect of Descurainia sophia seeds on isoproterenol-induced cardiomyopathy in rats by synergistically modulating the myosin motor

Astragaloside IV promotes pharmacological effect of Descurainia sophia seeds on isoproterenol-induced cardiomyopathy in rats by synergistically modulating the myosin motor

Descurainia sophia seeds (DS), Astragalus mongholicus (AM), and their formulas are widely used to treat heart failure caused by various cardiac diseases in traditional Chinese medicine practice. However, the molecular mechanism of action of DS and AM has not been completely understood. Herein, we fi...

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Bibliographic Details
Main Authors: Xingkai Liu, Qian Chen, Xuming Ji, Wanchen Yu, Tong Wang, Juanjuan Han, Shumu Li, Jianan Liu, Fangang Zeng, Yao Zhao, Yanyan Zhang, Qun Luo, Shijun Wang, Fuyi Wang
Format: Article
Language:English
Published: Frontiers Media S.A. 2022-08-01
Series:Frontiers in Pharmacology
Subjects:
astragaloside IV
cardiomyopathy
myosin
quantitative proteomics
Descurainia sophia seed
traditional Chinese medicine
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2022.939483/full

Internet

https://www.frontiersin.org/articles/10.3389/fphar.2022.939483/full

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