P-Glycoprotein and Androgen Receptor Expression Reveals Independence of Canine Prostate Cancer from Androgen Hormone Stimulation

P-Glycoprotein and Androgen Receptor Expression Reveals Independence of Canine Prostate Cancer from Androgen Hormone Stimulation

Canine prostate cancer (PC) is an aggressive disease, and dogs can be considered comparative models for human PC. In recent years, canine PC has been shown to resemble human castrate-resistant prostate cancer. The influx and efflux of testosterone in prostatic luminal cells are regulated by P-glycop...

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Bibliographic Details
Main Authors: Alexandre Matheus Baesso Cavalca, Andressa Brandi, Ricardo Henrique Fonseca-Alves, Renée Laufer-Amorim, Carlos Eduardo Fonseca-Alves
Format: Article
Language:English
Published: MDPI AG 2022-01-01
Series:International Journal of Molecular Sciences
Subjects:
ABCB1
testosterone
prostatic disease
comparative oncology
Online Access:https://www.mdpi.com/1422-0067/23/3/1163

Internet

https://www.mdpi.com/1422-0067/23/3/1163

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