Functional analysis of thyroid hormone receptor beta in Xenopus tropicalis founders using CRISPR-Cas

Functional analysis of thyroid hormone receptor beta in Xenopus tropicalis founders using CRISPR-Cas

Amphibians provide an ideal model to study the actions of thyroid hormone (TH) in animal development because TH signaling via two TH receptors, TRα and TRβ, is indispensable for amphibian metamorphosis. However, specific roles for the TRβ isoform in metamorphosis are poorly understood. To address th...

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Bibliographic Details
Main Authors: Yuto Sakane, Midori Iida, Takashi Hasebe, Satoshi Fujii, Daniel R. Buchholz, Atsuko Ishizuya-Oka, Takashi Yamamoto, Ken-ichi T. Suzuki
Format: Article
Language:English
Published: The Company of Biologists 2018-01-01
Series:Biology Open
Subjects:
Metamorphosis
Thyroid hormone receptor
CRISPR-Cas
Xenopus tropicalis
Online Access:http://bio.biologists.org/content/7/1/bio030338

Internet

http://bio.biologists.org/content/7/1/bio030338

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