Regulation of respiratory complex I assembly by FMN cofactor targeting

Regulation of respiratory complex I assembly by FMN cofactor targeting

Respiratory complex I plays a crucial role in the mitochondrial electron transport chain and shows promise as a therapeutic target for various human diseases. While most studies focus on inhibiting complex I at the Q-site, little is known about inhibitors targeting other sites within the complex. In...

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Bibliographic Details
Main Authors: Andrea Curtabbi, Adela Guarás, José Luis Cabrera-Alarcón, Maribel Rivero, Enrique Calvo, Marina Rosa-Moreno, Jesús Vázquez, Milagros Medina, José Antonio Enríquez
Format: Article
Language:English
Published: Elsevier 2024-02-01
Series:Redox Biology
Subjects:
Respiratory complex I
FMN
OXPHOS
DPI
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231723004020

Internet

http://www.sciencedirect.com/science/article/pii/S2213231723004020

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