HIF-1α facilitates glioma proliferation and invasion by activating pyroptosis signaling axis

Abstract Background HIF-1α is thought to be a novel regulator which contributes to carcinogenesis. However, the mechanism underlying the effect of HIF-1α in gliomas remains largely unknown. Methods In the research, we demonstrate that HIF-lα mRNA and protein levels are elevated in glioma cells. The...

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Bibliographic Details
Main Authors: Xin-Wei Wang, Hao Fu, Ya-Min Zhang
Format: Article
Language:English
Published: BMC 2024-05-01
Series:Chinese Neurosurgical Journal
Subjects:
Online Access:https://doi.org/10.1186/s41016-024-00366-3