microRNA are central players in anti- and profibrotic gene regulation during liver fibrosis.

microRNA are central players in anti- and profibrotic gene regulation during liver fibrosis.

miRNA are small noncoding RNA molecules that posttranscriptionally effect mRNA stability and translation by targeting the 3´-untranslated region (3`-UTR) of various transcripts. Thus, dysregulation of miRNA affects a wide range of cellular processes such as cell proliferation and differenti...

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Bibliographic Details
Main Authors: Andrea eNoetel, Monika eKwiecinski, Natalia eElfimova, Jia eHuang, Margarete eOdenthal
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-03-01
Series:Frontiers in Physiology
Subjects:
Fibrosis
Smad Proteins
microRNA
Extracellular Matrix (ECM)
Ap1
collagens
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00049/full

Internet

http://journal.frontiersin.org/Journal/10.3389/fphys.2012.00049/full

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