Feasibility and outcome of reproducible clinical interpretation of high-dimensional molecular data: a comparison of two molecular tumor boards

Feasibility and outcome of reproducible clinical interpretation of high-dimensional molecular data: a comparison of two molecular tumor boards

Abstract Background Structured and harmonized implementation of molecular tumor boards (MTB) for the clinical interpretation of molecular data presents a current challenge for precision oncology. Heterogeneity in the interpretation of molecular data was shown for patients even with a limited number...

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Bibliographic Details
Main Authors: Damian T. Rieke, Till de Bortoli, Peter Horak, Mario Lamping, Manuela Benary, Ivan Jelas, Gina Rüter, Johannes Berger, Marit Zettwitz, Niklas Kagelmann, Andreas Kind, Falk Fabian, Dieter Beule, Hanno Glimm, Benedikt Brors, Albrecht Stenzinger, Stefan Fröhling, Ulrich Keilholz
Format: Article
Language:English
Published: BMC 2022-10-01
Series:BMC Medicine
Subjects:
Precision oncology
Whole-exome sequencing
RNA-sequencing
Clinical interpretation
Targeted therapy
Molecular tumor board
Online Access:https://doi.org/10.1186/s12916-022-02560-5

Internet

https://doi.org/10.1186/s12916-022-02560-5

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