Promoter conservation in HDACs points to functional implications
Abstract Background Histone deacetylases (HDACs) are the proteins responsible for removing the acetyl group from lysine residues of core histones in chromosomes, a crucial component of gene regulation. Eleven known HDACs exist in humans and most other vertebrates. While the basic function of HDACs h...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
BMC
2019-07-01
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Series: | BMC Genomics |
Subjects: | |
Online Access: | http://link.springer.com/article/10.1186/s12864-019-5973-x |