Immunologic Basis for Long HCDR3s in Broadly Neutralizing Antibodies against HIV-1

A large panel of potent broadly neutralizing antibodies (bnAbs) against HIV-1 has been reported in recent years, raising hope for the design of an effective vaccine based on epitopes recognized by these protective antibodies. However, many of these bnAbs contain the feature of long heavy chain compl...

Full description

Bibliographic Details
Main Authors: Lei eYu, Yongjun eGuan
Format: Article
Language:English
Published: Frontiers Media S.A. 2014-06-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2014.00250/full