Early effects of dietary orotic acid upon liver lipid synthesis and bile cholesterol secretion in rats.
Dietary orotic acid is known to cause impaired fatty acid synthesis and increased cholesterol synthesis in rats. We found that the impaired fatty acid synthesis occurs during the first day of orotic acid feeding and, in studies with albumin-bound [1-14C]palmitic acid, an associated decrease in the r...
| Main Authors: | , |
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| Format: | Article |
| Language: | English |
| Published: |
Elsevier
1985-04-01
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| Series: | Journal of Lipid Research |
| Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520343637 |