EOS789, pan‐phosphate transporter inhibitor, ameliorates the progression of kidney injury in anti‐GBM‐induced glomerulonephritis rats

Abstract Hyperphosphatemia associated with chronic kidney disease (CKD) not only dysregulates mineral metabolism and bone diseases, but also strongly contributes to the progression of kidney disease itself. We have identified a novel drug for hyperphosphatemia, EOS789, that interacts with several so...

Full description

Bibliographic Details
Main Authors: Yoshinori Tsuboi, Yasuhiro Ichida, Atsuko Murai, Akira Maeda, Manami Iida, Atsuhiko Kato, Shuichi Ohtomo, Naoshi Horiba
Format: Article
Language:English
Published: Wiley 2022-06-01
Series:Pharmacology Research & Perspectives
Subjects:
Online Access:https://doi.org/10.1002/prp2.973