6-Shogaol Antagonizes the Adipocyte-Conditioned Medium-Initiated 5-Fluorouracil Resistance in Human Colorectal Cancer Cells through Controlling the SREBP-1 Level

The resistance of colorectal cancer (CRC) to chemotherapy, e.g., 5-fluorouracil (5-FU), is an impediment to successful cancer treatment. Although many mechanisms have been proposed to explain the occurrence of resistance, little is known concerning the role of the adipocyte-containing microenvironme...

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Bibliographic Details
Main Authors: Ko-Chao Lee, Kuen-Lin Wu, Chia-Kung Yen, Cheng-Nan Chen, Shun-Fu Chang, Wen-Shih Huang
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Life
Subjects:
Online Access:https://www.mdpi.com/2075-1729/11/10/1067