Genetic polymorphisms in tumour necrosis factor receptors (TNFRSF1A/1B) illustrate differential treatment response to TNFα inhibitors in patients with Crohn’s disease

BackgroundMonoclonal antibodies inhibiting tumour necrosis factor-α (TNFα) signalling pathway (anti-TNFα) have been widely used in Crohn’s disease (CD). However, treatment response varies among patients with CD and the clinical outcome is dependent on single nucleotide polymorphisms (SNP) in TNFα r...

詳細記述

書誌詳細
主要な著者: Ahmad Qasem, Saleh A Naser, Seela Ramesh
フォーマット: 論文
言語:English
出版事項: BMJ Publishing Group 2019-06-01
シリーズ:BMJ Open Gastroenterology