Genetic polymorphisms in tumour necrosis factor receptors (TNFRSF1A/1B) illustrate differential treatment response to TNFα inhibitors in patients with Crohn’s disease
BackgroundMonoclonal antibodies inhibiting tumour necrosis factor-α (TNFα) signalling pathway (anti-TNFα) have been widely used in Crohn’s disease (CD). However, treatment response varies among patients with CD and the clinical outcome is dependent on single nucleotide polymorphisms (SNP) in TNFα r...
主要な著者: | , , |
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フォーマット: | 論文 |
言語: | English |
出版事項: |
BMJ Publishing Group
2019-06-01
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シリーズ: | BMJ Open Gastroenterology |