Ultradeep sequencing of a human ultraconserved region reveals somatic and constitutional genomic instability.

Ultradeep sequencing of a human ultraconserved region reveals somatic and constitutional genomic instability.

Early detection of cancer-associated genomic instability is crucial, particularly in tumour types in which this instability represents the essential underlying mechanism of tumourigenesis. Currently used methods require the presence of already established neoplastic cells because they only detect cl...

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Bibliographic Details
Main Authors: Anna De Grassi, Cinzia Segala, Fabio Iannelli, Sara Volorio, Lucio Bertario, Paolo Radice, Loris Bernard, Francesca D Ciccarelli
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-01-01
Series:PLoS Biology
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20052272/?tool=EBI

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https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/20052272/?tool=EBI

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