DAKS1, a Kunitz Scaffold Peptide from the Venom Gland of <i>Deinagkistrodon acutus</i> Prevents Carotid-Artery and Middle-Cerebral-Artery Thrombosis via Targeting Factor XIa

Scaffold-based peptides (SBPs) are fragments of large proteins that are characterized by potent bioactivity, high thermostability, and low immunogenicity. Some SBPs have been approved by the FDA for human use. In the present study, we developed SBPs from the venom gland of <i>Deinagkistrodon a...

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Bibliographic Details
Main Authors: Zhiping Jia, Yunyang Liu, Xiaoru Ji, Yizheng Zheng, Zhengyang Li, Shuai Jiang, Hongjin Li, Yi Kong
Format: Article
Language:English
Published: MDPI AG 2021-09-01
Series:Pharmaceuticals
Subjects:
Online Access:https://www.mdpi.com/1424-8247/14/10/966