Geniposide plus chlorogenic acid reverses non-alcoholic steatohepatitis via regulation of gut microbiota and bile acid signaling in a mouse model in vivo

Geniposide plus chlorogenic acid reverses non-alcoholic steatohepatitis via regulation of gut microbiota and bile acid signaling in a mouse model in vivo

Background: Geniposide and chlorogenic acid are the major active ingredients in Yinchenhao Decoction and are widely used as herbal medicines in Asia. This study further assessed their effects on improvement of non-alcoholic steatohepatitis (NASH) in a mouse model and explored the underlying molecula...

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Bibliographic Details
Main Authors: Hongshan Li, Yingfei Xi, Xin Xin, Qin Feng, Yiyang Hu
Format: Article
Language:English
Published: Frontiers Media S.A. 2023-04-01
Series:Frontiers in Pharmacology
Subjects:
NASH
microbiota
bile acid
FXR
geniposide
chlorogenic acid
Online Access:https://www.frontiersin.org/articles/10.3389/fphar.2023.1148737/full

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https://www.frontiersin.org/articles/10.3389/fphar.2023.1148737/full

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