Exacerbating and reversing lysosomal storage diseases: from yeast to humans

Lysosomal storage diseases (LSDs) arise from monogenic deficiencies in lysosomal proteins and pathways and are characterized by a tissue-wide accumulation of a vast variety of macromolecules, normally specific to each genetic lesion. Strategies for treatment of LSDs commonly depend on reduction of t...

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Bibliographic Details
Main Authors: Tamayanthi Rajakumar, Andrew B. Munkacsi, Stephen L. Sturley
Format: Article
Language:English
Published: Shared Science Publishers OG 2017-08-01
Series:Microbial Cell
Subjects:
Online Access:http://microbialcell.com/researcharticles/exacerbating-and-reversing-lysosomal-storage-diseases-from-yeast-to-humans/