A Comprehensive Review of <i>HLA</i> and Severe Cutaneous Adverse Drug Reactions: Implication for Clinical Pharmacogenomics and Precision Medicine

A Comprehensive Review of <i>HLA</i> and Severe Cutaneous Adverse Drug Reactions: Implication for Clinical Pharmacogenomics and Precision Medicine

Human leukocyte antigen (<i>HLA</i>) encoded by the <i>HLA</i> gene is an important modulator for immune responses and drug hypersensitivity reactions as well. Genetic polymorphisms of <i>HLA</i> vary widely at population level and are responsible for developing s...

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Bibliographic Details
Main Authors: Chiraphat Kloypan, Napatrupron Koomdee, Patompong Satapornpong, Therdpong Tempark, Mohitosh Biswas, Chonlaphat Sukasem
Format: Article
Language:English
Published: MDPI AG 2021-10-01
Series:Pharmaceuticals
Subjects:
human leukocyte antigen
<i>HLA</i> genetic polymorphisms
SCARs
pharmacogenomics
precision medicine
Online Access:https://www.mdpi.com/1424-8247/14/11/1077

Internet

https://www.mdpi.com/1424-8247/14/11/1077

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