HOXB7 Overexpression Leads Triple-Negative Breast Cancer Cells to a Less Aggressive Phenotype

HOX genes appear to play a role in breast cancer progression in a molecular subtype-dependent way. The altered expression of HOXB7, for example, was reported to promote breast cancer progression in specific subtypes. Here we induced HOXB7 overexpression in MDA-MB-231 cells, a cellular model of the T...

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Bibliographic Details
Main Authors: Simone Aparecida de Bessa Garcia, Mafalda Araújo, Tiago Pereira, Renata Freitas
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Biomedicines
Subjects:
Online Access:https://www.mdpi.com/2227-9059/9/5/515